Which of the following is/are mechanism (s) to end neural transmission at the neuromuscular junction? Select all the correct answers. a. ACh is taken up by the axon terminal via endocytosis. b. ACh diffuses away from the synaptic cleft. c. ACh binds to ACh receptors. d. ACh is broken down into acetic acid and choline by the enzyme acetylcholinesterase (AChE).

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Biology

23 May, 20:10

Which of the following is/are mechanism (s) to end neural transmission at the neuromuscular junction? Select all the correct answers. a. ACh is taken up by the axon terminal via endocytosis. b. ACh diffuses away from the synaptic cleft. c. ACh binds to ACh receptors. d. ACh is broken down into acetic acid and choline by the enzyme acetylcholinesterase (AChE).

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Josue Sexton · Answer 1

d. ACh is broken down into acetic acid and choline by the enzyme acetylcholinesterase (AChE).

Explanation:

Following the dissociation from the receptor, acetylcholine has the particularity that is not recapture by the cells, but it's rapidly degraded by the the enzyme acetylcholinesterase, also present in the neuromuscular junction, ending the communication between the motor neuron and the muscle fiber.