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16 February, 22:13

A mutation causing an addition or a deletion of one base pair resulted in the production of a nonfunctional mutant protein. The sequences of the normal and mutant proteins are given below. Normal: Met - Tyr - His - Glu - Val Mutant: Met - Phe - Thr - Lys - Cys - Lys - Trp - Arg - ...

Was this mutation cause by an insertion or a deletion?

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  1. 16 February, 22:37
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    The mutation was caused as a result of deletion of one letter of the codon A from tyrosine leading a shift in the reading frame.

    Normal is

    Normal - Met - Tyr - His - Glu - Val

    Aug - Uac - Cac - Gaa - Gug

    When a is removed from Tyrosine codon we have a shift in the reading frame to form a mutant with a new codon and protein.

    Mutant - Met - Phe - Thr - Lys - Cys

    Aug - Ucc - Acg - Aag - Ugu

    Mutation is a sudden change in the genie of an organism that can be heritage by offspring from their parent.
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