Reword the following statement to make it true: The orderly flow of carbon through the TCA cycle is possible because each of the enzymes of the cycle is embedded in the inner mitochondrial membrane in such a manner that their order in the membrane is the same as their sequence in the cycle.

Question

Micaela Patton

Biology

17 June, 20:08

Reword the following statement to make it true: The orderly flow of carbon through the TCA cycle is possible because each of the enzymes of the cycle is embedded in the inner mitochondrial membrane in such a manner that their order in the membrane is the same as their sequence in the cycle.

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Answers (1)

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Nia Clark · Answer 1

The orderly flow of carbon through the TCA cycle is possible because of the substrate channeling between the enzymes of the cycle present in form of metabolons in mitochondrial matrix.

Explanation:

Enzymes of TCA cycle are not embedded in the inner mitochondrial membrane. The enzymes are present in the matrix of mitochondria. However, these enzymes are present in the form of multiple enzyme complexes called metabolons.

Substrate channeling through multienzyme complexes does not allow the product of one enzymatic reaction to leave the complex. Since the product of one enzyme is a substrate for another enzyme of metabolons, the order of the reactions is maintained.