Which of these statements about eicosanoid synthesis is true?

A) An early step in the path to thromboxanes is blocked by ibuprofen.

B) Arachidonate is derived mainly by hydrolysis of triacylglycerols.

C) Aspirin acts by blocking the synthesis of arachidonate.

D) Plants can synthesize leukotrienes, but humans cannot.

E) Thromboxanes are produced from arachidonate via the "linear" path.

A) An early step in the path to thromboxanes is blocked by ibuprofen.

Explanation:

Eicosanoids are signaling molecules that are produced by oxidation of arachidonic acid or other twenty-carbon essential fatty acid. Eicosanoids are involved in immune responses: they inhibit inflammation, allergy, fever, they also regulate pregnancy, childbirth, control cell growth ...

Synthesis of prostaglandins, prostacyclin and thromboxane (subfamilies of eicosanoids) is inhibited by aspirin and some anti-Inflammatory drugs such as ibuprofen and naproxen.