The proteome is all the proteins produced by an organism. The genome is the totality of all genes of an organism. If the proteome is much larger than the genome, which of the following statements would be accurate? This finding lends support to the one-gene, one-enzyme hypothesis. Noncoding DNA is important in determining the proteome. At least in some cases, a single gene must code for more than one protein. The number of monomeric subunits found in proteins is fewer than the number of monomeric subunits found in genes.

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Delgado

Biology

3 July, 13:47

The proteome is all the proteins produced by an organism. The genome is the totality of all genes of an organism. If the proteome is much larger than the genome, which of the following statements would be accurate? This finding lends support to the one-gene, one-enzyme hypothesis. Noncoding DNA is important in determining the proteome. At least in some cases, a single gene must code for more than one protein. The number of monomeric subunits found in proteins is fewer than the number of monomeric subunits found in genes.

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Elisabeth · Answer 1

At least in some cases, a single gene must code for more than one protein

Explanation:

A single gene can code more than one protein and it is done by the process of alternative splicing. Alternative splicing enables the excision, splicing of different introns and even the splicing of exons. For example, if there are 3 exons in the pre-mRNA, after the splicing, mature mRNA can contain all 3 exons or only exon 1 and 3.

In different cells, genes are differentially expressed (and differentially spliced) depending on the tissue type.