Mutations are A) heritable changes in the sequence of DNA bases that produce an observable phenotype. B) heritable changes in the sequence of DNA bases. C) mistakes in the incorporation of amino acids into proteins. D) heritable changes in the mRNA of an organism. E) None of the above

Answer: Option B) heritable changes in the sequence of DNA bases.

Explanation:

Mutations are permanent changes in the DNA sequence that makes up a gene. Gene mutations can be inherited from a parent or acquired during lifetime. So, mutations passed down from parents to offspring are called hereditary mutations or germ-line mutation.

And also, not all mutations produce observable phenotype, especially the changes that do not occur in the genes or that give similar amino acids as in the case of silent mutation.