Ask Question
15 December, 05:03

The mutation resulting in sickle cell disease changes one base pair of dna so that a codon now codes for a different amino acid

+2
Answers (1)
  1. 15 December, 05:22
    0
    Answer: Missense mutation

    Explanation:

    In sickle cell the glutamic acid in the 6th position of the beta chain of HbA (normal haemoglobin) is change to valine in HbS (sickle cell haemoglobin). This occur when there's a single nucleotide mutation. The (A) nucleotide in the condon (GAG) of glutamic acid is substituted for a (T) nucleotide. This single nucleotide substitution converts a glutamic acid codon (GAG) to a valine codon (GTG), which leads to polymerization of haemoglobin molecules in red blood cells. This cause a distortion of cell to a sickle shape.
Know the Answer?
Not Sure About the Answer?
Find an answer to your question 👍 “The mutation resulting in sickle cell disease changes one base pair of dna so that a codon now codes for a different amino acid ...” in 📗 Biology if the answers seem to be not correct or there’s no answer. Try a smart search to find answers to similar questions.
Search for Other Answers