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19 August, 21:55

Which of the following frame shift mutations might be expected to have the least impact on an organism

A) a deletion of 2 nucleotides near the beginning of the gene

B) an insertion of 3 nucleotides in the middle of the gene

C) a deletion of four nucleotides near the end of the gene

D) an insertion of 5 nucleotides at a genes promoter site

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  1. 19 August, 22:05
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    B) an insertion of 3 nucleotides in the middle of the gene

    This will have the least impact as it will not shift the overall reading frame as it will still be read as the same triplet codon, it may add an amino acid however on replication the complementary strand which wont have this sequence would allow for self correction of the DNA.
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