nutritional deficiencies interfere with the cell metabolism and tissue structure. look up rickets in your textbook or other resource and describe how rickets affects the extracellular matrix of bone and describe how this change in extracellular matrix causes symptoms of rickets.

Rickets is caused as a result of vitamin D deficiency. The role of vitamin D in the body is its significance in the absorption of phosphorus and calcium from the gut. Consequently, phosphorus and calcium in the blood is absorbed in the extracellular matrix of bone hence giving them strength. Therefore, deficiency of vitamin D results to soft bones that are a symptom of rickets.