Frederick Griffith infected mice with a combination of dead R and live S bacterial strains. What was the outcome, and why did it occur?

The mice will live. Transformation was not required.

The mice will die. Transformation of genetic material from R to S was required.

The mice will live. Transformation of genetic material from S to R was required.

The mice will die. Transformation was not required.

The correct answer will be option-The mice will die. Transformation of genetic material from R to S was required.

Explanation:

Frederick Griffith performed an experiment on the mouse using two strains of the Streptococcus pneumonia which are R (rough avirulent strain) and S (smooth-virulent strain).

In the experiment when he injected the live S bacteria with dead R bacteria, the mice died, opposite of the expected result that mice would not die. This amazed Griffith and he concluded that some transformation of the bacteria has happened due to which the mice died. The R bacteria became S bacteria (virulent) due to the transformation which was proved later that the bacteria took the DNA of the dead S bacteria from the surrounding.

Thus, the selected option is the correct answer.