Doctors have found a DNA marker that predicts the inheritance of a deadly disease, ALS. The band of markers labelled "C" shows the pattern inherited by people with the disease. One member of the Green family, the father, has ALS. His four children have been tested and the results are shown here. To inherit the disease, you must inherit all markers. Will any of Mr. Green's children have the disease? Explain.

Question

Mattie Gonzales

Biology

3 February, 20:07

Doctors have found a DNA marker that predicts the inheritance of a deadly disease, ALS. The band of markers labelled "C" shows the pattern inherited by people with the disease. One member of the Green family, the father, has ALS. His four children have been tested and the results are shown here. To inherit the disease, you must inherit all markers. Will any of Mr. Green's children have the disease? Explain.

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Answers (2)

Know the Answer?

Miya · Answer 1

D) No. The markers show that Mr. Green is not the father of the children

Kason Allison · Answer 2

Full Question:

Doctors have found a DNA marker that predicts the inheritance of a deadly disease, ALS. The band of markers labelled "C" shows the pattern inherited by people with the disease. One member of the Green family, the father, has ALS. His four children have been tested and the results are shown here. To inherit the disease, you must inherit all markers. Will any of Mr. Green's children have the disease? Explain.

Maybe. Child #1 has all but one of the markers for ALS.

No. The markers show that Mr. Green is not the father of the children.

Yes. Child #1 has the markers for the disease.

No. None of the children have all of the markers for ALS.

Answer:

No, none of the children of Mr Green will have all the markers for ALS.

Option D

Explanation:

ALS or the amyotrophic lateral sclerosis is a neural disease that is mainly of etiological cause, but sometimes it is inherited and then, it can lead to Juvenile Motor Neuron Disease. Here in this disease, the muscles slowly become stiffened and the feedback response is very much delayed from the brain. When inherited, it's an autosomal recessive disease. As it's autosomal recessive disease, both the alleles present of this gene needs to be mutated allele to manifest this disease.

In Mr Green's family, the person has the disease, but there's no history of this disease in the Mother's heredity. So mother is completely normal, and this results the kids to have a heterozygous trait. This therefore makes them the carrier of ALS, not the patients of ALS.