Arrange the events in the order that they occur during DNA replication. Tiles. Helicase unzips DNA to separate strands. Polymerase synthesizes new DNA strands. Topoisomerase unwinds the coiled DNA. The new strands are glued using ligase. Primase lays down short RNA strands.

DNA exists in a coiled form in order for it to take up a smaller volume in the cell so that is why the first thing is that it needs to be unwound by topoisomerase. Then each piece is made up of two strands that must be separated as they need to be copied separately, so next the helicase unzips the DNA. DNA polymerase needs to have something to build off so because DNA can be synthesized, the Primase needs to make an RNA "primer". DNA is then synthesized but because it cannot synthesize the whole chromosome in one piece, after DNA synthesis, the ligase must glue the shorter pieces together to make the entire chromosome. Correct Order 1. Topoisomerase unwinds the coiled DNA 2. Helicase unzips DNA to separate strands 3. Primase lays down short RNA strands 4. Polymerase synthesizes new DNA strands 5. The new strands are glued using ligase