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6 December, 15:04

During denaturation of DNA, which of the following happens?

Hydrogen bonds between complementary bases break.

Phosphodiester bonds break within the sugar-phosphate backbone.

Hydrogen bonds within the sugar-phosphate backbone break.

Phosphodiester bonds between complementary bases break.

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Answers (1)
  1. 6 December, 15:13
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    Option (1).

    Explanation:

    Denaturation may be defined as the process by which DNA loses its biological activity. Treatment of DNA with temperature or treating the DNA with strong acid or base can cause DNA denaturation.

    Denaturation allows the breakage of hydrogen bonds. The adenine is bonded with thymine with two hydrogen bonds and cytosine with guanine comprise of three hydrogen bonds. The breakage of hydrogen bonds between the complementary base pairs disrupts the DNA structure.

    Thus, the correct answer is option (1).
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