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22 January, 17:20

Which of the following claims about the TYR, TRP2, and TRP1 mammalian genes is most likely to be accurate?

a-The TYR, TRP2, and TRP1 genes are located next to each other on a single chromosome and are organized into an operon.

b-The TYR, TRP2, and TRP1 genes may be located on different chromosomes but are activated by the same transcription factor.

c-The TYR, TRP2, and TRP1 genes are identical genes since they are activated by the same transcription factor.

d-The TYR, TRP2, and TRP1 genes may be located on different chromosomes but with identical operator sequences.

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  1. 22 January, 17:22
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    The TYR, TRP2, and TRP1 genes are located next to each other on a single chromosome and are organized into an operon is most likely to be accurate.

    The option a is correct.

    Explanation:

    The genes for the Tyrosinase, TRP2 and TRP1 are located on the same chromosome and are operons. These are operons because they are controlled by same transcription factors on mRNA.

    Tyrosinase enzyme is important for the synthesis of melanin, eye pigments and hair colour. The synthesis of all these is completed in three distinct reactions catalysed by TRP1, TRP2 and Tyr genes. These work as operon and the protein product is almost 40% similar of the three genes.

    The amount of melanin production depends on tyrosinase enzyme activity of all the three genes.

    The genetic regulation is done by operons.
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