Using your knowledge of the digestive system, explain why taking GHR-15 orally would not provide any therapeutic benefit

The GHR-15 protein is considered to be a protein that, like all others, is made up of amino acids, which when ingested orally, stomach acids, and especially HCl, denature the protein and break the basic structure of this protein. generating the destruction of it.

Explanation:

This natural protein is a protein that encourages the release of growth hormone.

Today the parenteral or injectable route is considered to be the best route of administration, unless adequate measures are taken, such as some chemical changes, as happens in some derivatives of GHR-15.

The correct answer is "GHR-15 is a naturally occurring protein, therefore it would be degrade it if it is taken orally".

Explanation:

GHR-15 is an hormone releaser that elevates the levels of human growth hormone by stimulating the pituitary gland. GHR-15 is a naturally occurring protein, therefore if GHR-15 is taken orally it would not provide any therapeutic benefit because the digestive system would degrade it with gastric acid and the proteasome pathway before it could perform its biological activity. There are some formulations of GHR-15 that are taken orally but they are formulated accordingly to allow this feature.