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14 May, 20:37

Why are transport proteins multipass rather than single-pass integral membrane proteins?

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  1. 14 May, 21:02
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    Transport proteins multi-pass so that multiple alpha helices can form a hydrophilic pore that is able to diffuse small molecules. If transport proteins were single-passing, the alpha helix would not have a core with a diameter large enough to diffuse solutes.

    Multi-pass membrane proteins loop in and out, while single-pass membrane proteins cross the membrane once.
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