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30 April, 19:17

A circular molecule of DNA contains 1 million base pairs. If the DNA synthesis at a replication fork occurs at a rate of 100,000 nucleotides per minute, how much time will theta replication require to completely replicate the molecule, assuming that theta replication is bidirectional?

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  1. 30 April, 19:42
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    5 minutes

    Explanation:

    1. In bidirectional replication; there are two replication forks, and each proceeding at a rate of 100,000 (as given in the question) nucleotides per minute.

    2. So, by the given rate of replication, we can calculate that, it would require 5 minutes for the circular DNA molecule to be replicated by bidirectional replication because each fork synthesize 500,000 nucleotides in 5 minutes (100,000 per minute) (as given, in 5 minutes * 100,000 nucleotides per minute = 500,000 and by 2 forks = 1,000,000) within the time period.
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