By what mechanism does PI-3 phosphate promote activation of protein kinase B (PKB) ?

a. recruiting PKB to the plasma membrane

b. recruiting the activating kinase PDK1 to the plasma membrane

c. releasing inhibition of the catalytic site by the PH domain

d. the first and second answers are correct

e. all of the above

Question

Pranav

Biology

29 June, 01:54

By what mechanism does PI-3 phosphate promote activation of protein kinase B (PKB) ?

a. recruiting PKB to the plasma membrane

b. recruiting the activating kinase PDK1 to the plasma membrane

c. releasing inhibition of the catalytic site by the PH domain

d. the first and second answers are correct

e. all of the above

+4

Answers (1)

Know the Answer?

Dario Mosley · Answer 1

The answer is letter E. ALL THE ABOVE

Explanation:

The mechanisms are: recruiting PKB to the plasma membrane, recruiting the activating kinase PDK1 to the plasma membrane, and releasing inhibition of the catalytic site by the PH domain.