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10 May, 11:35

The Vmax of muscle glycogen phosphorylase is much larger than that of liver. What do we call enzymes that carry out the same reaction, but do it with different kinetics? Why does it make sense that the Vmax of the muscle enzyme is higher than that of the liver?

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  1. 10 May, 11:41
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    Isozymes

    Explanation:

    A) Isozymes are the enzymes that differ in their structure and kinetics but catalyze the same reaction. Glycogen phosphorylase in liver and muscle are isozymes.

    B) ATP are required in higher concentration by actively working muscle (higher glycolysis) and as the glycogen phosphorylase in muscle alternatively produce the glucose-6-phosphate for glycolysis, so it has higher Vmax value in muscle.

    Glycogen phosphorylase in liver converts the glycogen to glucose to increase blood glucose level.
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