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16 June, 08:47

What would happen to NADH levels in a cell in the first few seconds after a drug has poisoned the enzyme that combines acetyl CoA and oxaloacetate to form citrate

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  1. 16 June, 09:14
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    The correct answer is - The level of NADH will decrease

    Explanation:

    In the first step of the citric acid cycle or Krebs cycle, the enzyme citrate synthase catalyses the reaction in which two-carbon Acetyl CoA combines with four-carbon oxaloacetic acid to form a six-carbon compound citric acid.

    If action of the enzyme citrate synthase is inhibited by poisoning, then the product citrate will not formed. As a result further oxidation process will not be occur, thus 6 out of 10 NADH wiil not be produced.
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