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18 October, 23:46

Sickle cell disease results from an amino acid change from Valentine to glutamic acid. The result of this amino acid change is a deformed hemoglobin protein that does not carry oxygen well. What type of genetic mutation caused the amino acid change in a person with sickle cell anemia?

a. frameshift mutation

b. silent mutation

c. nonsense mutation

d. missense mutation

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  1. 19 October, 00:16
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    D. Missense mutation.

    A - the whole protein would be off, not just one AA

    B - the disease wouldn’t occur

    C - nonsense would end up in a truncated protein ((so shorter protein)
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