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17 January, 15:13

The formation of pyrimidine dimers results from which of the following?

spontaneous errors by DNA polymerase

exposure to gamma radiation

exposure to ultraviolet radiation

exposure to intercalating agents

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  1. 17 January, 15:34
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    exposure to ultraviolet radiation is a correct answer.

    Explanation:

    Ultraviolet light exposure results in the formation of pyrimidine dimers. Ultraviolet radiation damage the DNA by resulting in chemical changes.

    Ultraviolet radiation is absorbed by the pyrimidine bases (cytosine and thymine in DNA) and result in the formation of covalent bonds between the succeeding bases.

    The formation of the pyrimidine dimers results in the distortions of DNA helix and disrupt the base-pairing during the replication of DNA which results in a mutation.
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