Rtks can activate the enzyme phosphoinositide 3-kinase, which phosphorylates inositol phospholipids. these phospholipids then:

Rtks can activate the enzyme phosphoinositide 3-kinase, which phosphorylates inositol phopholipids; these phospholipids then serves as docking sites that recruit specific intracellular signaling proteins to the plamsa membrane. RTKs may activate various pathways including; the MAP-kinae signalling module, the Ras signalling pathway, and the phospholipase C/inostol phospholipid signaling pathway.