Which is the first enzyme used in the production of cdna?

The first enzyme is reverse transcriptase. The concept of reverse transcription was much unknown at first. A reverse transcriptase is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. It is mainly associated with retroviruses. As it contradicted the central dogma of molecular biology, which states that DNA is convert into RNA, which is then translated into proteins.