Select ALL of the following that are directly used to control fatty acid oxidation in cells.

A. negative feedback regulation if free fatty acids accumulate

B. changing the activity of the acylcarnitine shuttle

C. targeting the acetyl-CoA transport shuttle in the mitochondrial membrane

D. altering the activity of the oxidoreductase enzymes in β-oxidation

Question

Maximo Goodwin

Biology

3 April, 02:57

Select ALL of the following that are directly used to control fatty acid oxidation in cells.

A. negative feedback regulation if free fatty acids accumulate

B. changing the activity of the acylcarnitine shuttle

C. targeting the acetyl-CoA transport shuttle in the mitochondrial membrane

D. altering the activity of the oxidoreductase enzymes in β-oxidation

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Answers (1)

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Archer · Answer 1

The correct statements are A negative feed back regulation if free fatty acid accumulate C targeting the acetyl CoA transport shuttle in the mitochondrial membrane

Explanation:

The beta oxidation of fatty acid can be regulated by several following ways.

A The accumulation of free fatty acids exerts negative feedback during beta oxidation of fatty acids. As oxidation of fatty acids result in the breakdown of complex fatty acids in free fatty acids and acetyl CoA, the accumulation of free fatty acids lowers the rate of beta oxidation of fatty acid.

C The targeting of end product of beta oxidation that is acetyl CoA to the mitochondrial membrane also regulates the beta oxidation pathway. Because more the transport of acetyl CoA to the mitochondrial membrane more will be the rate of fatty acid break down by beta oxidation.