Levofloxacin is a broad-spectrum antibiotic that inhibits DNA gyrase. What is the most likely reason it can kill bacteria.
A. It blocks prokaryotic DNA replication by preventing melting of the DNA double helix at the replication fork B. It blocks prokaryotic DNA replication by preventing unwinding of the super coils in the DNA double helix
C. It interferes with prokaryotic DNA replication by preventing fusion of Okazaki fragments
D. it blocks prokaryotic transcription by preventing unwinding of the DNA double helix during transcriptional initiation
E. it blocks prokaryotic transcription by preventing unwinding of the DNA double helix during transcriptional elongation
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