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29 December, 15:55

A scientist has been measuring the amount of a particular mRNA strand being produced by certain cells. He notes that although a large amount of the mRNA is produced, he is finding relatively little of the protein product that the RNA codes for. His assistant suggests that they look for the presence of microRNA (miRNA). What would be suggested by the presence of miRNAs

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  1. 29 December, 16:00
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    Micro RNA (miRNA)

    Explanation:

    miRNA are basically small non encoding RNA molecules which are encoded in the genome of plants, animals and viruses Site of miRNA synthesis is nucleus in the form of long RNA transcript They further form a RNA induced silencing complex (RISC) which generally inhibits translation of target mRNA or catalyze degradation of target mRNA Presence of miRNA suggests that if there is perfect complementary with mRNA then degradation of mRNA will occur and if there is imperfect complementary between them then it will suppress the mRNA translation and hence little of the protein product will be formed
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