An investigator planning to study behavioral changes during alcohol intoxication will pay subjects for 6 hours of testing that includes drinking a moderate level of alcohol consumption and completing several long, selfadministered written questionnaires. He plans to recruit
economically disadvantaged and homeless people. Which of the following is the most important for the investigator to address before submitting the protocol to the IRB?
A. Potential undue influence or coercion of subjects
B. Forms of advertising for subject recruitment
C. Literacy of research subjects
D. Method of payment to subjects
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