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27 March, 17:18

A client presents with chief complaints of unexplained weight gain and back pain from a compression fracture of the vertebrae. On assessment, there is truncal obesity with excessively thin extremities, a moon-shaped face, a buffalo hump, thin hair, and adult acne. The symptoms described are suggestive of what disease?

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  1. 27 March, 17:23
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    The correct answer is Cushing's Syndrome.

    Explanation:

    Cushing's syndrome, also known as hypercortisolism, is a disease caused by the increase in the hormone cortisol. This excess cortisol can be caused by various causes. The most common, which affects 60 or 70% of patients, is an adenoma in the pituitary gland; This form of the syndrome is specifically known as Cushing's disease. Other causes of Cushing's syndrome are tumors or abnormalities in the adrenal glands, chronic glucocorticoid use or excessive ACTH production caused by a pituitary adenoma. ACTH is the hormone, produced by the pituitary gland, that stimulates the adrenal glands to produce cortisol. This disorder was described by the American neurosurgeon doctor Harvey Cushing, who reported it in 1932.
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