What is the main difference between a prokaryotic cell and a eukaryotic cell? A prokaryotic cell has flagella, and a eukaryotic cell does not. A prokaryotic cell has ribosomes, and a eukaryotic cell does not. A eukaryotic cell has a cell wall, and a prokaryotic cell does not. A eukaryotic cell has a nucleus, and a prokaryotic cell does not.
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