Which of the following sequences is known as a Kiliani-Fischer chain elongation? Group of answer choices 1. CH3OH, H+, Δ 2. AgNO3, Δ 1. CN - 2. H2, Pd/BaSO4 3. H3O + 1. Fe3+, H2O2 2. Br2, H2O 3. Ca (OH) 2 1. NaBH4 2. H2O 3. Br2, H2O 1. acetic anhydride (excess), pyridine 2. CH3I (excess), Ag2O

Question

Camron Bond

Chemistry

25 April, 14:19

Which of the following sequences is known as a Kiliani-Fischer chain elongation? Group of answer choices 1. CH3OH, H+, Δ 2. AgNO3, Δ 1. CN - 2. H2, Pd/BaSO4 3. H3O + 1. Fe3+, H2O2 2. Br2, H2O 3. Ca (OH) 2 1. NaBH4 2. H2O 3. Br2, H2O 1. acetic anhydride (excess), pyridine 2. CH3I (excess), Ag2O

+1

Answers (1)

Know the Answer?

Eileen Brock · Answer 1

The correct option is: 1. CN - 2. H₂, Pd/BaSO₄ 3. H3O+

Explanation:

Kiliani-Fischer synthesis is a method used for the elongation of the carbon chain of an aldose sugar, by the addition of carbon to aldehyde end of the aldose sugar.

In this method, the aldose sugar is treated with HCN in the first step, followed by reduction with hydrogen (H₂) in the presence of palladium / barium sulfate (Pd/BaSO₄) as catalyst in second step and then hydrolyzed in third step, to give a mixture of two elongated diastereomeric aldose sugars, called epimers.