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6 January, 09:30

The wittig reaction involves coupling between a phosphonium ylide and a carbonyl-containing molecule. if a chemist wants to use the wittig reaction to synthesize 2-methyl-2-butene, which reactants should be used?

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  1. 6 January, 09:55
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    2-Methyl-2-butene can be synthesized using Wittig reaction in following steps;

    1) First of all react Bromoethane with Triphenylphosphine which will undergo SN² reaction to produce Phosphonium salt. Phoshonium salt on treatment with base gives Phosphorous Ylide.

    2) The ylide formed when treated with acetone forms a four membered ring intermediate, which readily rearranges to produce 2-methyl-2-butene and triphenylphosphine oxide.

    Result:

    Starting materials are ...

    1) Bromoethane

    2) Acetone

    3) Triphenyl phosphene
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