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20 December, 02:50

You suspect that a serious developmental disorder is due to a chromosome abnormality and prepare a karyotype from an affected individual. in analyzing the karyotype, how could you distinguish trisomy from a chromosome structural defect such as a duplication?

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  1. 20 December, 03:05
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    The difference is very easy. In trisomy there would always be one extra chromosome. On the other hand, in a duplication one chromosome would have two copies of a portion of the chromosome.
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