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29 September, 17:37

Imagine a cell with a semi-permeable membrane that is selective to K + ions only. The internal solution contains 100 mM KCl and the external solution contains 1 mM KCl. What equation would you use to determine the potential (EK) developed across the membrane?

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  1. 29 September, 17:53
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    Ek = (RT/zF) * ln ([k+]o/[K+]i)

    Explanation:

    R = gas constant (8.31 J/Kmol)

    T = Temperature (k)

    F = Faraday constant (9.65 * 10exp4 coulomb/mole)

    z = valence of the ion (1)

    [k+]o = Extracellular K concentration in mM

    [K+]i = Intracellular K concentration in mM

    ln = logarithm with base e
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