Classify the following specific inhibitors or inhibitor characteristics according to one of three types of inhibition: reversible competitive, reversible noncompetitev, or irrersible.

A) reversible comp

B) reversible noncomp

C) Irreversible

1. inhibitor binds covalently and permanently at active site.

2. inhibitor strucure resembles substrate structure

3. inhibitor binds noncovalently at site other than active site

4. inhibitor does not alter the max reaction rate

A inhibitor structure resembles substrate structure B inhibitor binds non covalently at site other than active site. C inhibitors bind covalently and permanently at active site.

Explanation:

A Reversible competitive inhibitors structurally resembles the substrate and competes with the substrate to bind to the active site of the target enzyme.

B Reversible noncompetitive inhibitors binds no covalently at site of the target enzyme that is different from the active site.

C irreversible inhibitors interacts very tightly to the active site of an enzyme by covalent bond which cannot be overcome.