Some of the enzymes that oxidize sugars to yield useable cellular energy (for example, ATP) are regulated by phosphorylation. For these enzymes, would you expect the inactive form to be the phosphorylated form or the dephosphorylated form? Explain your answer.

Question

Travis Gilmore

Chemistry

8 September, 19:21

Some of the enzymes that oxidize sugars to yield useable cellular energy (for example, ATP) are regulated by phosphorylation. For these enzymes, would you expect the inactive form to be the phosphorylated form or the dephosphorylated form? Explain your answer.

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Dylan Allen · Answer 1

The enzyme undergoes reaction and produces cellular energy is likely to be inactive when the enzyme is phosphorylated and active when the enzyme is dephosphorylated.

The reason for the above statement is that when there is a need for the ATP to the body, the enzyme must be active to produce the energy currency. Also, ATP in the body is the source of phosphate which it transfer to the proteins or other biological molecules.

In a case where ATP is plentiful in the body, the enzyme must be inactive or turned off via the transfer of the phosphate group. Thus, phosphorylated enzyme is inactive form.