Which amino acid would, when incorporated into a polypeptide chain (not at the N or C terminus), make the charge of the polypeptide more positive?

Question

Sterling Lloyd

Chemistry

24 July, 15:09

Which amino acid would, when incorporated into a polypeptide chain (not at the N or C terminus), make the charge of the polypeptide more positive?

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Answers (1)

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Kody Riley · Answer 1

Answer: Arginine.

Explanation: Arginine is an amino acid that is used for the biosynthesis of protein. It is made up of an α-amino group, an α-carboxylic acid group, & a side chain consisting of a 3-carbon aliphatic straight chain ending in a guanidino group. At physiological pH, the carboxylic acid is deprotonated (-COO-), the amino group is protonated (-NH3+), and the guanidino group is also protonated to give the guanidinium form (-C - (NH2) 2+), making arginine a charged, aliphatic amino acid.