A reconstituted solution containing 500 mg of ganciclovir in 20 ml of sterile water for injection is added to 500 ml of 5% dextrose in water. the infusion is to be administered over 2 hours. if the infusion set delivers 15 drops/ml, what should the flow rate be to administer the bag over the designated time interval?

Question

Alana Howard

Chemistry

6 June, 16:41

A reconstituted solution containing 500 mg of ganciclovir in 20 ml of sterile water for injection is added to 500 ml of 5% dextrose in water. the infusion is to be administered over 2 hours. if the infusion set delivers 15 drops/ml, what should the flow rate be to administer the bag over the designated time interval?

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Gerardo Galloway · Answer 1

The flow of rate that you are asked for is the number of drops per time unit.

Usually it is counted the number of drops per minute, so I will aim to that.

1) Calculate the total volume.

Assuming additive volumes = > final volume = volume of sterile water + volume of the dextrose solution

Final volume = 20 ml + 500 ml = 520 ml.

2) Calculate the number of drops in 520 ml, given that there are 15 drops in 1 ml:

=> 520 ml * 15 drops / ml = 7800 drops.

3) That must be administered over 2 hours, which is 120 minutes.

So, calculate the flow rate as the number of drops divided by the time in minutes:

flow rate = 7800 drops / 120 minutes = 65 drops / minute.

Answer: 65 drops / minute