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1 June, 16:08

Carbon dioxide affects O2binding to Hb by: a) CO2forming iron carbonate with the heme-iron atom. b) Hb competing with carbonic anhydride for CO2. c) directly binding to heme-Fe in the oxygen binding site of hemoglobin. d) forming HCO3 - that combines with H + to increase CO2binding. e) forming H + HCO3 - where the H is an antagonist to oxygen binding to Hb.

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  1. 1 June, 16:21
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    The correct answer is c) directly binding to heme Fe in the oxygen binding site of the hemoglobin.

    Explanation:

    Carbon dioxide is the waste product of cellular respiration. Carbon dioxide bind to hemoglobin to form carbaminohemoglobin in which the hemoglobin exist as T state or Tensed state.

    Carbon dioxide interact with the oxygen binding site of hemoglobin thus decreasing the affinity of hemoglobin for oxygen.
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