A group of letters that have a specific meaning and can appear at the beginning of many different words is called a suffix.

The given statement is false.

Explanation:

We are given the following statement which we are to determine whether it is true or false:

'A group of letters that have a specific meaning and can appear at the beginning of many different words is called a suffix'.

The above statement is false because it is a description of prefix.

While a suffix is like a prefix but it only comes at the end of the word.