What problems emerge from the theory of directed panspermia?

Directed Panspermia is the transport of microorganisms in space to be used as new species in areas where there is no life.

The problems or objections are that it may interfere with local life. That is, the new microorganisms may fight with the existing ones for resoruces or they may infect them in order to survive.

Another problem is that space should be clean for new scientific studies.