How does Anne's tone address her opinions on mrs. van Daan?

Anne's tone changes to rather scornful and even indictive when addressing Mrs. Van Daan.

Explanation:

Anne's tone changes to rather scornful and even indictive when addressing Mrs. Van Daan because Anne's diary makes it clear that she considers Mrs Van Daan to be a constant complainer-moody, panicky as well as neurotic reason been that She is the source of many disturbances and much bickering in the secret annex in which the Frank and Van Daan families are forced to share.