What effect did the introduction of smallbox have in America

the introduction of smallpox killed an estimate of 90 percent of native americans at that time which was alot of deaths they died because they never met the virus and their immunity was new to it it caused a disaster in the lives of native americans

Smallpox which was contracted from Europeans and Africans, was supposed to have led to the abundant amount of deaths of Native Americans. Nearly 95% of the Native American population was decimated due to smallpox.