Border ruffians who is disrupted Kansas before its state hood where from

Missouri

This event is referred to as Bleeding Kansas and took place when Kansas was voting on whether or not to be a slave state.

Kansas had been granted popular sovereignty meaning they were allowed to vote on whether or not the state would be a slave or free state. Abolitionists flooded the state to encourage citizens of Kansas to vote to be a free state. However, Missouri being a slave state was concerned about being located next to a free state, so people from Missouri crossed the border and attempted to vote for slave status. While there, they got into large riots with abolitionists hence the name "Bleeding Kansas".