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18 December, 15:10

Which of the following significant changes to a protocol could be administratively approved (in principle) by VVC? A. A change from non-survival to survival surgeryB. A change in the principal investigatorC. A change in the specific objectives for the projectD. A change in the analgesic agent administered

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  1. 18 December, 15:17
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    Answer: "Why are we wasting energy trying to distinguish between a minor amendment and

    a major amendment?" asked Joanie Green,

    the new IACUC senior administrator at

    Great Eastern University. It seemed to her

    that if there was a request to add a procedure to a protocol it was to be considered

    an amendment, nothing more or less. "Are

    you saying that adding a small subcutaneous

    implant is as important as adding a cardiac

    valve replacement?" asked Bob Thorne, a

    clinical veterinarian. Green responded that

    it had nothing to do with the level of difficulty or risk to an animal, but whether

    or not there was a need for IACUC review.
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