The Cherokee were the most assimilated of all the Native American tribes.

The answer is "True".

The Cherokee are one of the native groups of the Southeastern Woodlands, one of the biggest Native American clans. Preceding the eighteenth century, they were packed in southwestern North Carolina, southeastern Tennessee, and the tips of western South Carolina and northeastern Georgia.

The name Cherokee is a Local American infant name. In Local American the name Cherokee means: Individuals of another discourse.