What process did Columbus and his followers begin?

Colombus and his followers began the process of the Exploration of Americas

Columbus was an italian explorer who completed four voyage across the Atlantic Ocean. He and his followers discover the Existence of America in 1492 during these voyages

Columbus and his followers brought upon many processes. One of which was the exploration of both the South and the North part of America and their subsequent besettlement of both. Another thing was slow and gradual genocide that was brought upon to both Americas again by the conquistadors, who conquered this region in God's name.