A drug that inhibits angiotensin converting enzyme (ACE) may lead to all of the following except

a) reduction of blood pressure.

b) increased fluid retention.

c) less secretion of aldosterone.

d) decreased sodium reabsorption.

e) increased urinary loss of sodium.

Answer: Option A

Explanation:

As soon as ACE is activated, it tends to indirectly increase blood pressure body content and sodium. Obliviously, it increases blood pressure and option A says opposite. The best answer is option A

c) less secretion of aldosterone.

Explanation:

ACE inhibitors prevent the conversion of decapeptide angiotensin I into angiotensin II, the substance that normally controls vasoconstriction and decreases protein kinase C. This leads to the relaxation of blood vessels and increase in blood flow, that's why they're used to treat illnesses associated with high blood pressure. This decreasing of blood pressure stimulates the adrenal gland releasing aldosterone and increasing Na + reabsorption.

Considering this information we can conclude that c) less secretion of aldosterone is the correct answer because ACE inhibitors decrease blood pressure and this increases the aldosterone secretion, contrary to the option.

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