How do you think european exploration will affect native americans?

Diseases.

Explanation:

Like any indigenous uninterrupted group of people, coming into contact with foreign entities always poses the risk of contacting diseases due to the fact fact these people live or have lived in isolation for a long period of time. Diseases common to European explorers at that time such as Chicken pox, influenza and small pox were a risk to the natives due to their low immunity.

This isn't enough to answer the question