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2 March, 09:57

What explanation is generally given for lethality of monosomic individuals?

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  1. 2 March, 10:02
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    Monosomy may unmask recesive lethals that are tolerated in heterozygotes carrying the wild type allele. Monosomy is when a cell has one chromosome less then a normal number. Monosomy of autosomal chromosomes rarely occur in live born patients. The example of monosomy of sex chromosome is Turner syndrome.
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